Rhodococcus equi Infection after Alemtuzumab Therapy for T-cell Prolymphocytic Leukemia

نویسندگان

  • Jan J. Meeuse
  • Herman G. Sprenger
  • Sander van Assen
  • Dominique Leduc
  • Simon M.G.J. Daenen
  • Jan P. Arends
  • Tjip S. van der Werf
چکیده

Rhodococcus equi, mainly known from veterinary medicine as a pathogen in domestic animals, can also cause infections in immunocompromised humans, especially in those with defects in cellular immunity. Alemtuzumab, an anti-CD52 monoclonal antibody, causes lymphocytopenia by eliminating CD52-positive cells. We report a patient in whom Rhodococcus equi infection developed after alemtuzumab therapy.

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عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2007